For maximum accessibility, choose Fedora's Mate spin, found at https://spins.fedoraproject.org/mate-compiz/download/index.html[the Fedora Mate download page].
Follow xref:creating-and-using-a-live-installation-image.adoc#proc_creating-and-using-live-usb[the guide on flashing the downloaded image to a flash drive or DVD], and prepare to restart the computer to begin the installation.
To install Fedora Mate, hereafter referred to as just "Fedora", you'll need to start your computer with the installer's drive set as the drive the computer starts from.
Consult your computer's manual for how to do this, but it is usually done by pressing the power button while the computer is still turned off, then quickly pressing a key, like F2, F8, F10, or F12, rapidly until the "boot manager" appears.
You'll need either sighted assistance, or an app on a smart phone that continuously reads text (like Seeing AI on the Apple App Store, or Google Lookout from the Google Play store), in order to somewhat know what's on the screen of this menu.
If you have no other drives, local or network, connected to the computer, you may be able to press Down arrow or Right arrow several times to get to the last item of the menu, which should be your external drive, and press Enter to boot from it.
In text fields, use the Left and Right arrow keys to navigate by character, Control with Left and Right arrow to navigate by word, and Up and Down arrow to navigate by line.
Use Home to go to the beginning of the line, End to go to the end of the line, and Control Home and Control End to go to the beginning and end of a text field.
Use arrow keys to navigate lists, and the Space bar or Enter key to activate buttons, check boxes, and so on.